Researchers have targeted the use of catalytic methods to reduce CO2 to single carbon intermediates, then to follow with biological up-conversion to multi-carbon compounds. In this project, Montana State researchers developed electrochemical reactor components with laterally graded pore structure to aid in reaction distribution when the reactor is scaled-up. Project partners integrated these components into the reactor and determined performance. Finally, the recent discovery of a novel C-C bond forming reaction that is orthogonal to central metabolism and requires fewer enzymes and reaction steps was utilized to develop bioproducts. Lee Spangler of Montana State University led the team that created this presentation on project progress and milestones ahead, for DOE Project Peer Review.